지역사회 거주 노인의 인지장애에 따른 우울장애 빈도
Frequency of Depressive Disorders According to Cognitive Continuum in the Elderly Living in the Community
전경자 ( June Kyung-Ja ) – Kangwon National University Hospital Department of Psychiatry
한지원 ( Han Ji-Won ) – Seoul National University Bundang Hospital Department of Neuropsychiatry
김기웅 ( Kim Ki-Woong ) – Seoul National University Bundang Hospital Department of Psychiatry
곽경필 ( Kwak Kyung-Phil ) – Dongguk University Gyeongju Hospital Department of Psychiatry
김봉조 ( Kim Bong-Jo ) – Gyeongsang National University School of Medicine Department of Psychiatry
김신겸 ( Kim Shin-Gyeom ) – Soonchunhyang University Bucheon Hospital Department of Neuropsychiatry
김정란 ( Kim Jeong-Lan ) – Chungnam National University School of Medicine Department of Psychiatry
문석우 ( Moon Seok-Woo ) – Konkuk University School of Medicine Konkuk University Chungju Hospital Department of Psychiatry
박준혁 ( Park Joon-Hyuk ) – Jeju National University Hospital Department of Neuropsychiatry
윤종철 ( Youn Jong-Chul ) – Kyunggi Provincial Hospital for the Elderly Department of Neuropsychiatry
이동영 ( Lee Dong-Young ) – Seoul National University College of Medicine Department of Psychiatry
이동우 ( Lee Dong-Woo ) – Inje University Sanggye Paik Hospital Department of Neuropsychiatry
이석범 ( Lee Seok-Bum ) – Dankook University Hospital Department of Psychiatry
이정재 ( Lee Jung-Jae ) – Dankook University Hospital Department of Psychiatry
정현강 ( Jeong Hyun-Ghang ) – Korea University College of Medicine Korea University Guro Hospital Department of Psychiatry
김태희 ( Kim Tae-Hui ) – Yonsei University Wonju Severance Christian Hospital Department of Psychiatry
박재영 ( Park Jae-Young ) – Seoul National University Bundang Hospital Department of Neuropsychiatry
정현 ( Jeong Hyeon ) – Seoul National University Bundang Hospital Department of Neuropsychiatry
류승호 ( Ryu Seung-Ho ) – Konkuk University School of Medicine Konkuk University Chungju Hospital Department of Psychiatry
주진형 ( Jhoo Jin-Hyeong ) – Kangwon National University Hospital Department of Psychiatry
방법 : 2010 년 11 월부터 2012년 10월까지 6,262 명의 기본 연구 대상자를 대상으로 국내 최초의 다기관 인구 기반 전향적 코호트 연구인 인지 노화 및 치매에 대한 한국의 종단 연구를 기반으로 등록했습니다. MCI, 치매, 주요 우울 장애 (MDD), 경미한 우울장애 (mDD) 및 서브 신드로 우울증 (SSD)의 진단은 적절한 진단 기준에 기초하여 치매에 대한 전문 지식을 가진 정신과 의사에 의해 이루어졌다.
결과 : 4,303 NC, 1,737 MCI, 222 치매가 등록되었습니다. MDD, mDD, SSD의 빈도는 치매에서 가장 높았고 NC에서 가장 낮았으며 세 그룹간에 유의 한 차이가있었습니다. MCI와 치매에서 승산 비는 치매에서 가장 높은 승산비를 보이는 NC에 비해 크게 증가했습니다.
결론 : 지역 사회 거주 노인의 MCI와 치매는 치매에서 가장 높은 연관성 경향을 보이는 다양한 유형의 우울 장애와 유의하게 연관되어 있음을 제안합니다.
Abstract
Methods: 6,262 baseline study subjects from November 2010 through October 2012 were enrolled based on the Korean longitudinal study on cognitive aging and dementia which is the first nationwide multi-center population based prospective cohort study in Korea. Diagnosis of MCI, dementia, major depressive disorder (MDD), minor depressive disorder (mDD) and subsyndromal depression (SSD) was made by psychiatrists with expertise in dementia based on the appropriate diagnostic criteria.
Results: 4,303 NC, 1,737 MCI, 222 dementia were enrolled. The frequency of MDD, mDD, SSD were highest in dementia and lowest in NC and showed significant difference among three groups. The odds ratio also increased significantly in MCI and dementia compared with NC showing highest odds ratio in dementia.
Conclusion: Our findings propose that MCI and dementia in the community dwelling elderly were significantly associated
with various types of depressive disorders showing highest association tendency in dementia.
